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With the help of a healthy diet and regular exercise, people with obesity can be successfully treated with Adipex-P, a brand-name version of the generic phentermine medication. It is a short-term oral medication that can be taken for a few weeks at a time. Adipex-P is an appetite suppressant and a central nervous system stimulant. As of 1959, the US Food and Drug Administration had approved the use of phentermine, which is the active ingredient in Adipex, for medical purposes. Generic and brand versions are both supported. With more than 2 million prescriptions issued each year, Adipex-P is one of the most commonly prescribed medications of its kind

UsesĀ of Adipex-P

In the short term, Adipex-P can aid in weight loss, but only if calorie reduction and exercise are not enough, and it can also be used in conjunction with a low-calorie diet.

Adipex-P is approved by the FDA for use for a maximum of 12 weeks, but the most weight loss occurs in the first two weeks. Weight loss continues through the sixth month, but at a slower rate than in the previous months.

No one should take Adipex-P if they have a history of drug abuse, have an allergy to sympathomimetic amine drugs, have high thyroid function, have cardiovascular disease, or are pregnant.

Mechanism of Action

Adipex-P, like its parent compound amphetamine, is an agonist of the TAAR1 receptor, which is similar to TAAR1. Neurochemical efflux can be facilitated by activating TAAR1 in monoamine neurons. Norepinephrine and serotonin and dopamine are also released into synapses at clinical doses of Adipex-P, but to a lesser extent.

Substituted amphetamines, such as Adipex-P, cause the release of monoamines from VMAT2.

Reduced hunger is the primary mechanism by which Adipex-P works to treat obesity. The lateral hypothalamic nucleus, ventromedial nucleus, and arcuate nucleus all play a role in this process of cognitive processing. The medication causes fat cells to break down stored fat by releasing epinephrine and norepinephrine outside the brain.

Adverse Effects

Adipex-P has been linked to pulmonary hypertension and heart disease in a small number of cases. Tolerance to the medication is common, but the chances of becoming dependent on or addicted to it are extremely low.

Medication users should exercise caution when driving or operating heavy machinery.

When taken with Adipex-P, alcohol has a negative impact. Before you buy Adipex-P online, make an appointment with your doctor to go over all the possible side effects and precautions.

Pregnant women have yet to be shown to be safe from the medication, as no evidence or studies have shown.

Other adverse effects of Adipex-P include:

  • High blood pressure, angina, a myocardial infarction (heart attack), cardiac arrest (heart failure), and other cardiovascular problems can occur as a result.
  • Overstimulation, nervousness, restlessness, tremor, insomnia, headache, dizziness, hallucinations, and depression are all symptoms of central nervous system effects.
  • Constipation, diarrhoea, nausea, vomiting, cramps, and diarrhoea are just a few of the symptoms that can develop when something goes wrong in the digestive tract.
  • There are also possible side effects such as a rash or impotence or difficulty urinating or swelling of the face.


Adipex-P contains phentermine that interacts with several drugs to decrease their effects:

  • Clonidine
  • Methyldopa
  • Guanethidine

Phentermine has a synergistic effect with hypothyroidism medications. Avoid taking Adipex-P if you know it will interact with another medication you are taking.